Swagelok® Regulators for Life Sciences


Reliable pressure control is essential to the safe operation of your process and utility lines. When selecting a regulator, you are not just looking for the right size – you're looking for a set of capabilities. 

Browse popular selections for the industry: 

Sanitary Pressure Reducing Regulators 


These sanitary regulators are designed for medium high pressure and are available with sanitary clamp end connections. The PRS series pressure regulator features a handle knob for pressure adjustment, 316L stainless steel metal components and FDA / USP Class VI compliant EPDM seals. The Sanitary line of regulators is best used with clean / dry gases for purging, tank blanketing and other process support applications.

  • Diaphragm sensing mechanism and spring-load pressure control
  • Large diaphragm-to-seat ratio for increased sensitivity
  • 316L Stainless Steel material construction with FDA/USP Class VI compliant seals
  • ½, 1 and 1 ½ Inch sanitary clamp end connections
  • Special cleaning to ASTM G93 Level C
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RHPS Series Pressure Regulators


RHPS series regulators provide a variety of options including spring-loaded and dome-loaded for both pressure-reducing and back-pressure regulator models, as well as specialty regulators specifically designed for pharmaceutical applications. All possess FDA / USP Class VI compliant EPDM seals.

  • Diaphragm or Piston Sensing for various application.
  • Spring load or Dome load mechanism.
  • 21 CFR FDA approved seals with no lubricant option available.
  • Various end connection including NPT, ASME 16.5 Flange and EN 1092 (DIN) Flange.
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K Series Regulators


  • Convoluted, non-perforated diaphragm ensures greater sensitivity with longer life.
  • Diaphragm and Piston Sensing Mechanism available.
  • 21 CFR FDA-approved seals with no lubricant option available.

Notable for you: 

The KPR series is a compact regulator with excellent accuracy, sensitivity, and set point pressure stability.

  • Convoluted, non-perforated diaphragm
  • Metal-to-metal diaphragm seal
  • Low internal volume
  • Two-piece cap design provides linear load on the diaphragm seal
  • High-flow, dual-gauze type filter in inlet ports
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Browse the full breadth of Swagelok catalog products